Today I was picked on by Dr. Raj to present the clinical features, and treatment on the 7 lysosomal storage diseases. I thought I presnted the material in due confidence, as I've read-and re-read the material multiple times (modesty aside, I actually enjoyed the lipid and enzymatic processes that were deficiency-related). However, Dr. Raj (my Biochemistry Professor for this Lipids and Amino Acids (this block term) managed to put in rather assymetrical questions that came out of no where. He didn't ask me quesitons on the prognosis, diagnosis, symptomatic features and possible treatment options (which I knew), but instead, asked me on the academic aspect of the enzymatic deficiencies.
He asked me about structural conformation. GAH!!!
His question to me was the structural conformation of the HGPRT enzyme~(Hypoxanthine Guanine Phosphoribosal Pyrophosphate Transferase), which has a role in in the salvation pathway of Purine-Pyramidical synthesis. Main features of this is that if there is a deficiency of HGPRT enzyme, we observe mental retardation, cerebral palsy, hyperurecemia, and compulsive self mutilations due to ataxic spasms.
One thing I realize about Medical Professors is that they love to put anyone on the spot. And simulate medical situations of the 'unexpected' possibilities.
I love Biochemistry, and I really like how Dr. Raj stimulates our thinking ability. Our sympathetic nervous reactions, lol. Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=12266.0