By Katie Alcock Science reporter, BBC News
People who think more about whether they are right have more cells in an area of the brain known as the frontal lobes.
UK scientists, writing in Science, looked at how brain size varied depending on how much people thought about decisions.
But a nationwide survey recently found that some people think too much about life.
These people have poorer memories, and they may also be depressed.
Stephen Fleming, a member of the University College London (UCL) team that carried out the research, said: "Imagine you're on a game show such as 'Who Wants to Be a Millionaire' and you're uncertain of your answer. You can use that knowledge to ask the audience, ask for help."
The London group asked 32 volunteers to make difficult decisions. They had to look at two very similar black and grey pictures and say which one had a lighter spot.
They then had to say just how sure they were of their answer, on a scale of one to six. Although it was hard to tell the difference, the pictures were adjusted to make sure that no-one found the task harder than anyone else.
People who were more sure of their answer had more brain cells in the front-most part of the brain - known as the anterior prefrontal cortex.
This part of the brain has been linked to many brain and mental disorders, including autism. Previous studies have looked at how this area functions while people make real time decisions, but not at differences between individuals.
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