Health - Role of Pyruvate Dehydrogenase Kinase 4 in Regulating PDH Activation during Acute Muscle Contraction

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Role of Pyruvate Dehydrogenase Kinase 4 in Regulating PDH Activation during Acute Muscle Contraction

Introduction The regulation of carbohydrate oxidative metabolism in mammalian tissues is controlled by the multi-enzyme pyruvate dehydrogenase (PDH) complex. PDH catalyzes the irre versible decarboxylation of pyruvate and subsequent acetyl addition to form acetyl-CoA, providing a source of ... (Publication: Applied Physiology, Nutrition, and Metabolism)

Source: Role of Pyruvate Dehydrogenase Kinase 4 in Regulating PDH Activation during Acute Muscle Contraction
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