Science News: Altered miRNA Expression as Diagnostics and Therapeutics for Adrenocortical Carcinomas

[MikeLigalig.com]

Altered miRNA Expression as Diagnostics and Therapeutics for Adrenocortical Carcinomas

This technology describes that altered human miRNA expression such as miRNA-483 and miRNA 100 can accurately predict if a patient's adrenal cortex tumor is benign or malignant.  Adrenocortical carcinomas (ACC) are rare but aggressive cancers and typically have a poor prognosis.  Currently, there are limited options for molecular diagnosis to distinguish malignant tumors from benign tumors of this type.  As a result there are few treatment strategies for ACC.

Preliminary results suggest that altering the expression of this miRNA in ACC cells can effect cancer cell growth.  Therefore, inhibiting a miRNA may serve as a therapeutic option for ACC.

Source: Altered miRNA Expression as Diagnostics and Therapeutics for Adrenocortical Carcinomas