MikeLigalig.com

Scientific Opinion on ChromoPrecise(R) cellular bound chromium yeast added for nutritional purposes as a source of chromium in food supplements and the bioavailability of chromium from this source
         
         The Panel on Food Additives and Nutrient Sources added to Food (ANS)  provides  a scientific opinion re-evaluating the safety of ChromoPrecise® cellular bound chromium  yeast added for nutritional  purposes as a source of chromium in food supplements and the bioavailability of  chromium from this source. ChromoPrecise®  is a yeast preparation with an enriched trivalent chromium content, obtained by  culture of Saccharomyces cerevisiae in the presence of chromium chloride. A daily  intake of 100 µg  chromium(III). There are limited data on the nature  and identity of the organic chromium(III) compounds contained in  chromium-enriched yeast and on their toxicokinetic and toxicodynamic behaviour  in the body. Overall, the Panel  concluded that  the bioavailability in man of chromium from chromium-enriched yeast  is potentially up  to approximately ten times higher than that of chromium from chromium chloride. A NOAEL of 2500  mg/kg bw/day ChromoPrecise® was identified in a 90-day feeding study in rats; no  evidence of adverse effects of chromium yeasts were reported in other animal  studies investigating the effects of dietary supplementation with chromium  yeast. ChromoPrecise® chromium yeast was non-genotoxic in a range of in vitro genotoxicity studies. Although  no information was available on the chronic toxicity, carcinogenicity or  reproductive toxicity of ChromoPrecise® chromium yeast,  the ANS Panel has previously concluded that trivalent chromium is not  carcinogenic, and limited  data on other chromium yeasts provide no evidence of an effect on reproductive endpoints.  No adverse effects have been reported in clinical efficacy trials with chromium  yeasts. The Panel concluded that the use of ChromoPrecise® chromium yeast in food  supplements is not of concern, despite the lack of data on the nature and identity  of the organic chromium(III) compounds contained in the product, provided that  the intake does not exceed 250 μg/day, as recommended  by the WHO.
        © European Food Safety Authority, 2012
        
         Scientific Opinion on ChromoPrecise(R) cellular bound chromium yeast added for nutritional purposes as a source of chromium in food supplements and the bioavailability of chromium from this source

Source: Scientific Opinion on ChromoPrecise(R) cellular bound chromium yeast added for nutritional purposes as a source of chromium in food supplements and the bioavailability of chromium from this source

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=59616.0