MikeLigalig.com

Standing at 23 inches tall â€" and weighing in at just 11 pounds â€" Jyoti Amge is no ordinary teenager. In fact, the 14-year-old is the world's smallest girl, according to the Indian Book of Records.

Amge has a form of dwarfism called achondroplasia, which affects an estimated one out of every 25,000 births and occurs in all races.

But, her tiny size hasn't hampered her spirit one bit.

The teenager told Britain's Sunday Mirror that she enjoys the celebrity status her height has brought her.

"I am proud of being small. I love the attention I get," she told the paper.

"I'm just the same as other people. I eat like you, dream like you. I don't feel any different."

According to the Mayo Clinic, about 70 percent of all people with dwarfism have achondroplasia, which causes disproportionately short stature.

This disorder usually results in:

â€" An adult height of approximately 4 feet

â€" An average-size trunk

â€" Short arms and legs, with particularly short upper arms and legs

â€" Short fingers, often with a wide separation between the middle and ring fingers

â€" Limited mobility at the elbows

â€" A disproportionately large head, with a prominent forehead and flattened bridge of the nose

Despite all this, Amge is just like any other teenager.

She loves listening to music, watching DVDs and attends the local high school in her town of Nagpur, India, where she sits side-by-side with classmates of her own age.

"When Jyoti was born, she seemed quite normal," her mother, Ranjana, 45, told the Sunday Mirror.

"We came to know about her disorder when she was five. We consulted a specialist and he said she will be this size all of her life. Jyoti is small, yet cute, and we love her very much."

As for the future â€" it’s wide open.

For the most part, people with this form of dwarfism have normal intelligence and lifespan â€" and this very ambitious teenager intends to take full advantage of all her talents.

"I would like to work in a big city like Mumbai, act in films and travel to London and America," she said.

She has even recently recorded an album with her favorite Indian pop star, Mike Singh, according to the report.



with her family

Kamay ong baya sya ni Mahal.

bitaw murag sila ra

Gamay jod sya.

http://www.youtube.com/watch?v=YLUyWKQrZxw

gamay lagi sya orchs.lol

naa ba diay smallest girl Adtin nga mahimong daku! lol.

ako lang  giklaro basin midako diay na ug kalit beh.

weee.. nagpakita na gyod ka sa imong avatar Adtin..

Hmm ma inlove gyod si musiclover ana og samot sa music.lol

hahaha.pataka man ka Bulak

Aw kinsa man diay nang  naa sa imong avatar? imong kaluha or imong kalag.

lol.ako man gikuha ug balik na wa naman pud beh.ikaw ra ang nakakita ato.

aw kung mao ako ra jod diay saksi sa tanan,

buotan tingale ka kay himsog man ka og kalag sa imong avatar.lol.

hahaha.kita diay ka ato?maayo kay natulog pa ang uban  wa sila kita ato.yehey

iswear. smallest jud.

Unsa kaha kung magtapad silang Mahal?

murag  igsoon sa  gawas

Quote from: Sigbin II on April 09, 2008, 07:21:27 PM
Unsa kaha kung magtapad silang Mahal?

mas gamay pa na siyang mahal oi.

oi laina ani, maajo pa si mahal kay naminjo na.

little sister ni mahal kung magtapad sila

Quote from: Vito Andoline on April 09, 2008, 07:24:38 PM
murag  igsoon sa  gawas

aw abi kog igsoon nimo sa gawas Vito,lol.

Quote from: Brownman on April 09, 2008, 07:31:36 PM
oi laina ani, maajo pa si mahal kay naminjo na.

Brother Brown, kinsa diay nabana ni Mahal? hu wala nakoy update da!

Quote from: bulak on April 09, 2008, 07:51:42 PM

Quote from: Brownman on April 09, 2008, 07:31:36 PM
oi laina ani, maajo pa si mahal kay naminjo na.

Brother Brown, kinsa diay nabana ni Mahal? hu wala nakoy update da!

Sis Bulak musta diha tanan, ako tung natan awan sa TB itsurahan man sab tung
laki murag lingin raman siguro ang gui apas sa laki kay mahal.

Luoya pod niya.. so dile lagi pod parihas niya kadak-a ang iyang nabana?
Kay diha man to siyay loveteam sa una, si mura man tingale to.

Nakalimot naman ko oi.

Di man to sila love team ni Mura kay ang ilang gipagawas kay baje man kuno si Mura.  Luoy 'tawn si Mura.

Si Jimboy man tingali ang na bana ni Mahal?

mura ug si mahal.unsa man  pud ug iapil nato si dagol.lol

mao bitaw, ngil ad bitaw pud ning ubang tawo bisag wa mahigugma
mag kis kis man pud pag naay camera, basin mag showbiz
siguro pud tong lakiha.

kabalo naman ka kinabuhi sa artista, boyet. ana jud na. kiss2x bisan wa ganahi. hehehe

Quote from: Sigbin II on April 09, 2008, 08:11:04 PM
Di man to sila love team ni Mura kay ang ilang gipagawas kay baje man kuno si Mura.  Luoy 'tawn si Mura.

Ay mao ba Paul, pupariha raba to sila og nawong abi man ko og sila ay magdayon, shalan ba diay nga babaye diay si Mura?

At least sikat man bitaw sila.

Laki tos Mura pero ilang gipagawas nga baje.

Quote from: Ginger on April 09, 2008, 08:14:35 PM

kabalo naman ka kinabuhi sa artista, boyet. ana jud na. kiss2x bisan wa ganahi. hehehe

sus bitaw arang hiki hiki siguro nila sa off cam Hase, murag Jimboy
bitaw ngan adtong dyuwa ni mahal.

MAo ba, so thanks for the info Paul, hmmm nganong dile naman lang god sila maoy nagdayon kay looy pod si mahal kung pangwartahan ra anang iyang nabana.

mao man pud iyang palad BUlak.wa man tay mahimo gawas kung putlon nato iyang palad.lol

Quote from: Vito Andoline on April 09, 2008, 08:22:53 PM
mao man pud iyang palad BUlak.wa man tay mahimo gawas kung putlon nato iyang palad.lol

mao nay gikanta ni  Jerome Sala na gulong ng palad ang buhay ay hmm

Hay Vito, wala gyod koy dag-anan nimo. Bitaw sakto  man ka pero hu! luag ra gihapon.LOL.

Quote from: bulak on April 09, 2008, 08:47:09 PM
Hay Vito, wala gyod koy dag-anan nimo. Bitaw sakto  man ka pero hu! luag ra gihapon.LOL.

gihimo man ko nimo na turnilyo oi.dawaton gihapon basta imong kalipay Bulak  akong kasakit

ka nice sa iya attitude.. happy girl despite her condition..

Quote from: bulak on April 09, 2008, 08:47:09 PM
Hay Vito, wala gyod koy dag-anan nimo. Bitaw sakto  man ka pero hu! luag ra gihapon.LOL.

Unsa may naluag diay ha?Karon pa man ko kabalik oy.hehehe

Quote from: orChids on April 09, 2008, 09:01:43 PM

Quote from: bulak on April 09, 2008, 08:47:09 PM
Hay Vito, wala gyod koy dag-anan nimo. Bitaw sakto  man ka pero hu! luag ra gihapon.LOL.

Unsa may naluag diay ha?Karon pa man ko kabalik oy.hehehe

pangutan-a si  Bulak orchs sya ra man ang gagama

Ngek,sa naluag?hahahaha unsa diay ang naluag god Vitz?

Da si Vito usahay man god dile mutuhay ika estorya, niluag ang roska og gamay,lol.

Quote from: bulak on April 09, 2008, 09:10:02 PM
Da si Vito usahay man god dile mutuhay ika estorya, niluag ang roska og gamay,lol.

na mao na ni persa siguro nimong mingawa sa akoa noh?miss you Bulak

hehehehe tua na vits! o yeah na pud dha!

Quote from: bulak on April 09, 2008, 09:10:02 PM
Da si Vito usahay man god dile mutuhay ika estorya, niluag ang roska og gamay,lol.

Saon usahay kabuhi-on man god,giingnan bitaw ug pahukot sa dorow aron maulian ang naluag nga roska.ahahahah peace Vitz.

Quote from: orChids on April 09, 2008, 09:15:35 PM

Quote from: bulak on April 09, 2008, 09:10:02 PM
Da si Vito usahay man god dile mutuhay ika estorya, niluag ang roska og gamay,lol.

Saon usahay kabuhi-on man god,giingnan bitaw ug pahukot sa dorow aron maulian ang naluag nga roska.ahahahah peace Vitz.

huhuhu wa pa tawn ko na  tililing oi.murag  di pa

Quote from: bulak on April 09, 2008, 05:18:33 PM


Standing at 23 inches tall â€" and weighing in at just 11 pounds â€" Jyoti Amge is no ordinary teenager. In fact, the 14-year-old is the world's smallest girl, according to the Indian Book of Records.

Amge has a form of dwarfism called achondroplasia, which affects an estimated one out of every 25,000 births and occurs in all races.

But, her tiny size hasn't hampered her spirit one bit.

The teenager told Britain's Sunday Mirror that she enjoys the celebrity status her height has brought her.

"I am proud of being small. I love the attention I get," she told the paper.

"I'm just the same as other people. I eat like you, dream like you. I don't feel any different."

According to the Mayo Clinic, about 70 percent of all people with dwarfism have achondroplasia, which causes disproportionately short stature.

This disorder usually results in:

â€" An adult height of approximately 4 feet

â€" An average-size trunk

â€" Short arms and legs, with particularly short upper arms and legs

â€" Short fingers, often with a wide separation between the middle and ring fingers

â€" Limited mobility at the elbows

â€" A disproportionately large head, with a prominent forehead and flattened bridge of the nose

Despite all this, Amge is just like any other teenager.

She loves listening to music, watching DVDs and attends the local high school in her town of Nagpur, India, where she sits side-by-side with classmates of her own age.

"When Jyoti was born, she seemed quite normal," her mother, Ranjana, 45, told the Sunday Mirror.

"We came to know about her disorder when she was five. We consulted a specialist and he said she will be this size all of her life. Jyoti is small, yet cute, and we love her very much."

As for the future â€" it’s wide open.

For the most part, people with this form of dwarfism have normal intelligence and lifespan â€" and this very ambitious teenager intends to take full advantage of all her talents.

"I would like to work in a big city like Mumbai, act in films and travel to London and America," she said.

She has even recently recorded an album with her favorite Indian pop star, Mike Singh, according to the report.



with her family

This is a classic case of primordial dwarfism.

Its due to a mutanogenisis of the RNA polymerase II factors, which in turn mutate the ability of transcription in the DNA of the humanoid chromosome.

The mutation within the polymerase complex is due to a protein-to-protein inhibition or denaturation. Such a small genetic mistake, ushers in a trillion fold mutanogensis in the malformation of organismal growth.
What happens is that the RNA polymerase' structure is changed in that when the Tata-binding protein binds to the Tata Box in the promoter cortex, it is unable to allow the binding of the GCbox's SP1 protein subunit, which is responsible for binding with the general transcriptional factor 110, which therein is attached to the TBP(tata-binding rotein) through the TAFII250 transcription factor. Without this proper binding sequence, there is no manifestation of the pre-initiator complex, if there is no pre-initiator complex, there is no elongation, thus there is no transcription.

Any inhibition or lack of transcription of DNA transcript will mutate and alter the specific DNA sequence, which leads to phenotypic and genotypic mutation and abnormalities.

In this case, there was a lack of transcription of a genomic sequence that was responsible for the proper function of the AER (apical ectodermal ridge) within the limb, which is responsible for proper limb formation.

This is actually a perfect case study in a molecular biology or cellular biology course.

Gamaya niya oi, hapit gud sila magtupong sa iyang bag.

lame kuguson Cel, hahahha himos kaayu tan awon.

wala pa jod ko kakita og tinood nga ingana sa tv ra noon.

Quote from: bulak on April 10, 2008, 03:53:42 PM
lame kuguson Cel, hahahha himos kaayu tan awon.

wala pa jod ko kakita og tinood nga ingana sa tv ra noon.

mahadlok  gyud ko ug ingon ana Bulak.

hoy nganong mahadlok man ka nga  mamaak ba diay na sila..

di ko ganahan mura ug underworld.lol

Quote from: bulak on April 09, 2008, 05:18:33 PM


Standing at 23 inches tall â€" and weighing in at just 11 pounds â€" Jyoti Amge is no ordinary teenager. In fact, the 14-year-old is the world's smallest girl, according to the Indian Book of Records.

Amge has a form of dwarfism called achondroplasia, which affects an estimated one out of every 25,000 births and occurs in all races.

But, her tiny size hasn't hampered her spirit one bit.

The teenager told Britain's Sunday Mirror that she enjoys the celebrity status her height has brought her.

"I am proud of being small. I love the attention I get," she told the paper.

"I'm just the same as other people. I eat like you, dream like you. I don't feel any different."

According to the Mayo Clinic, about 70 percent of all people with dwarfism have achondroplasia, which causes disproportionately short stature.

This disorder usually results in:

â€" An adult height of approximately 4 feet

â€" An average-size trunk

â€" Short arms and legs, with particularly short upper arms and legs

â€" Short fingers, often with a wide separation between the middle and ring fingers

â€" Limited mobility at the elbows

â€" A disproportionately large head, with a prominent forehead and flattened bridge of the nose

Despite all this, Amge is just like any other teenager.

She loves listening to music, watching DVDs and attends the local high school in her town of Nagpur, India, where she sits side-by-side with classmates of her own age.

"When Jyoti was born, she seemed quite normal," her mother, Ranjana, 45, told the Sunday Mirror.

"We came to know about her disorder when she was five. We consulted a specialist and he said she will be this size all of her life. Jyoti is small, yet cute, and we love her very much."

As for the future â€" it’s wide open.

For the most part, people with this form of dwarfism have normal intelligence and lifespan â€" and this very ambitious teenager intends to take full advantage of all her talents.

"I would like to work in a big city like Mumbai, act in films and travel to London and America," she said.

She has even recently recorded an album with her favorite Indian pop star, Mike Singh, according to the report.



with her family

Pagkagamatoy na baji oi but she looks so happy!  Why man wa sya nag shoes anang last picture?  Nice kaayo iyang attire ana dah!

ka kiat ba nija ug hitsura!

she is pretty though...

hahahahhha

naa na daghan diri...

Naa jod,just take a look at me sometimes. hehehe

malipayun nga bata murag c mahal

Quote from: Vito Andoline on April 10, 2008, 09:28:29 PM
di ko ganahan mura ug underworld.lol

ngeh, la jud ko ka relate nganong na underworld ning girl.. ka cute ra niya ah!

Quote from: bulak on April 09, 2008, 05:56:49 PM
naa ba diay smallest girl Adtin nga mahimong daku! lol.

hahhahhahhahhah

Quote from: mr. bean on April 11, 2008, 05:31:12 PM

Quote from: bulak on April 09, 2008, 05:56:49 PM
naa ba diay smallest girl Adtin nga mahimong daku! lol.

hahhahhahhahhah

naa himoang big letter na  kay  sobra pa sa dako.lol

ah wala jod kay klaru Vito.. pagamay gamay rana pero og madat-ugan ka ana, mag-utnga man jod ka  ba.lol.

Quote from: bulak on April 11, 2008, 06:13:50 PM
ah wala jod kay klaru Vito.. pagamay gamay rana pero og madat-ugan ka ana, mag-utnga man jod ka  ba.lol.

hahahaha

Quote from: bulak on April 11, 2008, 06:13:50 PM
ah wala jod kay klaru Vito.. pagamay gamay rana pero og madat-ugan ka ana, mag-utnga man jod ka  ba.lol.

haha! may tama ka!

update photo

Quote from: bulak on April 10, 2008, 03:53:42 PM
lame kuguson Cel, hahahha himos kaayu tan awon.

wala pa jod ko kakita og tinood nga ingana sa tv ra noon.

Mao bitaw no, gaan ba kaha na siya?

Quote from: Vito Andoline on April 10, 2008, 09:28:29 PM
di ko ganahan mura ug underworld.lol

Pataka raman ka Ads, ngano gud tawon imo mana gitawag ug underworld.

Quote from: bulak on April 09, 2008, 05:18:33 PM

Standing at 23 inches tall â€" and weighing in at just 11 pounds â€" Jyoti Amge is no ordinary teenager. In fact, the 14-year-old is the world's smallest girl, according to the Indian Book of Records.

Amge has a form of dwarfism called achondroplasia, which affects an estimated one out of every 25,000 births and occurs in all races.

But, her tiny size hasn't hampered her spirit one bit.

The teenager told Britain's Sunday Mirror that she enjoys the celebrity status her height has brought her.

"I am proud of being small. I love the attention I get," she told the paper.

"I'm just the same as other people. I eat like you, dream like you. I don't feel any different."

According to the Mayo Clinic, about 70 percent of all people with dwarfism have achondroplasia, which causes disproportionately short stature.

This disorder usually results in:

â€" An adult height of approximately 4 feet

â€" An average-size trunk

â€" Short arms and legs, with particularly short upper arms and legs

â€" Short fingers, often with a wide separation between the middle and ring fingers

â€" Limited mobility at the elbows

â€" A disproportionately large head, with a prominent forehead and flattened bridge of the nose

Despite all this, Amge is just like any other teenager.

She loves listening to music, watching DVDs and attends the local high school in her town of Nagpur, India, where she sits side-by-side with classmates of her own age.

"When Jyoti was born, she seemed quite normal," her mother, Ranjana, 45, told the Sunday Mirror.

"We came to know about her disorder when she was five. We consulted a specialist and he said she will be this size all of her life. Jyoti is small, yet cute, and we love her very much."

As for the future â€" it’s wide open.

For the most part, people with this form of dwarfism have normal intelligence and lifespan â€" and this very ambitious teenager intends to take full advantage of all her talents.

"I would like to work in a big city like Mumbai, act in films and travel to London and America," she said.

She has even recently recorded an album with her favorite Indian pop star, Mike Singh, according to the report.



with her family

ay may-ong sad nawong ni mahal pariha sila dwarfism .....