Several people have been killed in a series of coordinated attacks targeting Mumbai sites popular with tourists and business people, according to police and CNN's sister network in India.
Ongoing battles between police and gunmen were reported at two five-star hotels by CNN-IBN.
Gunmen armed with automatic weapons and grenades attacked targets including the hotels, a cafe, and a train station, police say.
Maharashtra state government spokesman Bhushan Gagri said 78 people killed and about 200 wounded, while police confirmed 26 deaths.
The attacks included five shootouts and two grenade attacks, said a police officer who answered Mumbai's police control room line.
IBN reported ongoing gun battles at the Oberoi Hotel and the Taj Mahal Hotel -- both five-star hotels.
At least two explosions were reported at the Taj.
One witness told local reporters gunmen had tried to find people with U.S. or British passports.
IBN, quoting police sources, reported hostages were taken at the two hotels although Gagri told CNN he did not know about any hostages.
The attacks began about 2230 local time (1700 GMT) and more than two hours later witnesses were reporting new explosions and gunfire.
The targets include businesses frequented by international visitors in the city which is India's financial center.
CNN correspondent Andrew Stevens said: "We are getting reports of ongoing incidents at the railway station and the Oberoi Hotel.
"We do not know if this has reached its peak or if more attacks to come."
A local journalist told CNN he had seen evidence of an attack at the city's domestic airport, which is on the outskirts of the Mumbai.
IBN reported explosions at a gas station and inside a taxi on a dockside road.
Attacks were reported at the Taj and Oberoi hotels, the popular Café Leopold, and Cama Hospital, and the Chhatrapati Shivaji Terminus railway station.
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