Author Topic: What Dictates Male Fertility?  (Read 1070 times)

slackware

  • Only the strong can survive...
  • LUMINARY
  • ***
  • Posts: 4033
  • "Die as a hero or live long enough as a vallain?"
    • View Profile
What Dictates Male Fertility?
« on: July 03, 2007, 03:23:44 AM »
What Dictates Male Fertility? - An immune factor
By: Stefan Anitei, Science Editor - Softpedia


It is easy to blame it on the woman, but in 40 % of the couples, the man is the sterile part. Now, a team at the Feinstein Institute for Medical Research found an immune factor that regulates human semen, inducing fertility or sterility in a man.

The macrophage migration inhibitory factor (MIF) appears to be crucial in maturing sperm, to make it ready for reproduction. This discovery could lead to a new test for male fertility. The team collected semen samples from men three to five days after a sexual abstinence period.

The research pool
was made of 68 men with reproductive issues and 27 healthy controls, and the analyses were made without the identity of the owner being known. The individuals with infertility issues presented too high or too low MIF levels, while the healthy subjects had average values.

When supplementary MIF was added into lab dishes with normal sperm, their count and mobility dropped. In this case, MIF could be employed as a method of male contraception. The team has also developed a patent that can be employed to analyze MIF levels in order to forecast a man's fertility.

MIF is a crucial immune molecule, detected 40 years ago, and only recently found to be a pro-inflammatory chemical. It has been connected to many autoimmune and inflammatory conditions, like diabetes and sepsis. The Feinstein team recently discovered a critical zone on the MIF protein surface that induces the main inflammatory response. A chemical attacking that area could be employed to treat many conditions, such as septic shock, sepsis, rheumatoid arthritis and diabetes.

They developed a specific inhibitor, ISO-1, to match the pro-inflammatory area. In animal tests with sepsis, ISO-1 kills MIF’s potent inflammatory capacities and the animals survived with a once-fatal sepsis. In case of sepsis (an over-reactive and usually deadly immune response to a bacterial attack) MIF levels are 10 to 20 times over the normal. If MIF decreases, the patients' survival chances increase dramatically.

215,000 Americans die annually of sepsis, while another 500,000 survive the infection, but often with severe cardiovascular problems. MIF was found crucial in heart damage. The anti-MIF antibodies significantly increased cardiac performance during septic shock. MIF levels are also two times higher in autoimmune conditions like rheumatoid arthritis and diabetes.

The research team discovered that having high levels of MIF makes lab animals prone to diabetes, weeks earlier than expected. But MIF does not work by itself: it uses a network of molecules to trigger its pro-inflammatory effects. The Feinstein team aims to detect those recruit chemicals.

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=2283.0
"All that is needed for evil to succeed is, that decent human beings doing nothing". (Edmund Burke)

unionbank online loan application low interest, credit card, easy and fast approval

MikeLigalig.com

  • FOUNDER
  • Webmaster
  • *****
  • Posts: 33284
  • Please use the share icons below
    • View Profile
    • Book Your Tickets on a Budget
Re: What Dictates Male Fertility?
« Reply #1 on: March 07, 2012, 09:12:44 AM »
Is there any fruit drink or herbal concoction that could increase healthy sperm production?

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=2283.0
John 3:16-18 ESV
For God so loved the world, that he gave his only Son (Jesus Christ), that whoever believes in him should not perish but have eternal life. For God did not send his Son into the world to condemn the world, but in order that the world might be saved through him. Whoever believes in him is not condemned, but whoever does not believe is condemned already, because he has not believed in the name of the only Son of God.

👉 GET easy and FAST online loan at www.tala.com Philippines

Book tickets anywhere for planes, trains, boats, bus at www.12go.co

islander

  • SUPREME COURT
  • THE LEGEND
  • *****
  • Posts: 46867
  • If you're from Pluto, you're welcome.
    • View Profile
    • Book Your Travel Tickets
Re: What Dictates Male Fertility?
« Reply #2 on: March 07, 2012, 10:27:09 AM »
kakuyaw diay ning septic infection... abi ba nakog fertility is kuyog sa full moon. ;D

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=2283.0
Republic Act 8485 (Animal Welfare Act of 1998, Philippines), as amended and strengthened by House  Bill 6893 of 2013--- violation means a maximum of P250,000 fine with a corresponding three-year jail term and a minimum of P30,000 fine and six months imprisonment

Book your travel tickets anywhere in the world, go to www.12go.co

unionbank online loan application low interest, credit card, easy and fast approval

MikeLigalig.com

  • FOUNDER
  • Webmaster
  • *****
  • Posts: 33284
  • Please use the share icons below
    • View Profile
    • Book Your Tickets on a Budget
Re: What Dictates Male Fertility?
« Reply #3 on: March 07, 2012, 10:32:23 AM »
what is its relation with septic tank? :)

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=2283.0
John 3:16-18 ESV
For God so loved the world, that he gave his only Son (Jesus Christ), that whoever believes in him should not perish but have eternal life. For God did not send his Son into the world to condemn the world, but in order that the world might be saved through him. Whoever believes in him is not condemned, but whoever does not believe is condemned already, because he has not believed in the name of the only Son of God.

👉 GET easy and FAST online loan at www.tala.com Philippines

Book tickets anywhere for planes, trains, boats, bus at www.12go.co

islander

  • SUPREME COURT
  • THE LEGEND
  • *****
  • Posts: 46867
  • If you're from Pluto, you're welcome.
    • View Profile
    • Book Your Travel Tickets
Re: What Dictates Male Fertility?
« Reply #4 on: March 07, 2012, 10:38:56 AM »
what is its relation with septic tank? :)

until lorenz comes, we have to make do with the fact that both septic infection and septic tank are dangerous, and they're everywhere. ;D

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=2283.0
Republic Act 8485 (Animal Welfare Act of 1998, Philippines), as amended and strengthened by House  Bill 6893 of 2013--- violation means a maximum of P250,000 fine with a corresponding three-year jail term and a minimum of P30,000 fine and six months imprisonment

Book your travel tickets anywhere in the world, go to www.12go.co

Lorenzo

  • SUPREME COURT
  • THE LEGEND
  • *****
  • Posts: 54226
  • Be the change you want to see in the world...
    • View Profile
Re: What Dictates Male Fertility?
« Reply #5 on: March 07, 2012, 11:47:35 AM »
lol ! bwahahaha!

septic infection refers to a condition called septicemia (or sepsis). it is when there is a bolus of bacteria in the blood.

both , septic tank and sepsis, are bad because they "stink" up the environment. septic tank stink up the actual external environment, and sepsis stinks up the interstitial milieu.

:)

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=2283.0
www.trip.com - Hassle-free planning of your next trip

Lorenzo

  • SUPREME COURT
  • THE LEGEND
  • *****
  • Posts: 54226
  • Be the change you want to see in the world...
    • View Profile
Re: What Dictates Male Fertility?
« Reply #6 on: March 08, 2012, 01:20:09 PM »
What dictates male fertility?

Answer: Testosterone

Linkback: https://tubagbohol.mikeligalig.com/index.php?topic=2283.0
www.trip.com - Hassle-free planning of your next trip

unionbank online loan application low interest, credit card, easy and fast approval

Tags: