Author Topic: Smoking causes gene damage in minutes  (Read 1471 times)

hubag bohol

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Smoking causes gene damage in minutes
« on: January 17, 2011, 08:21:09 AM »
Sat Jan 15, 9:17 pm ET


WASHINGTON (AFP) – Those first few puffs on a cigarette can within minutes cause genetic damage linked to cancer, US scientists said in a study released.

In fact, researchers said the "effect is so fast that it's equivalent to injecting the substance directly into the bloodstream," in findings described as a "stark warning" to those who smoke.

The study is the first on humans to track how substances in tobacco cause DNA damage, and appears in the peer-reviewed journal Chemical Research in Toxicology, issued by the American Chemical Society.

Using 12 volunteer smokers, scientists tracked pollutants called PAHs, or polycyclic aromatic hydrocarbons, that are carried in tobacco smoke and can also be found in coal-burning plants and in charred barbecue food.

They followed one particular type -- phenanthrene, which is found in cigarette smoke -- through the blood and saw it form a toxic substance that is known to "trash DNA, causing mutations that can cause cancer," the study said.

"The smokers developed maximum levels of the substance in a time frame that surprised even the researchers: just 15-30 minutes after the volunteers finished smoking," the study said.

"These results are significant because PAH diol epoxides react readily with DNA, induce mutations, and are considered to be ultimate carcinogens of multiple PAH in cigarette smoke," the study said.

Lead scientist Stephen Hecht said the study is unique because it examines the effects of inhaling cigarette smoke, without interference from other sources of harm such as pollution or a poor diet.

"The results reported here should serve as a stark warning to those who are considering starting to smoke cigarettes," Hecht said.

Lung cancer kills about 3,000 people around the world each day, and 90 percent of those deaths are attributable to cigarette smoking.

The research was funded by the National Cancer Institute.


http://news.yahoo.com/s/afp/healthussmoking



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Lorenzo

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Re: Smoking causes gene damage in minutes
« Reply #1 on: January 17, 2011, 11:52:40 PM »
Nong, great article. The gene that is altered , Delta-P53 Gene, is also a tumor suppressor gene. Smoking destroys these tumor suppressor genes, hence, in cases of long-term smokers, their lung cancer development is due to the destruction of their P-53 tumor suppressor genes.

With the destruction of the body's P53 tumor suppressor genes, tumors / cancers can develop in the breast, lungs, pancreas, colon, liver, etc. Global effect.



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islander

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Re: Smoking causes gene damage in minutes
« Reply #2 on: January 17, 2011, 11:57:35 PM »
so why are cigarettes, majority of which are american brands, still sold and readily available worldwide?  why aren't these banned as harmful drugs?  is the tobacco lobby that influential?

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Lorenzo

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Re: Smoking causes gene damage in minutes
« Reply #3 on: January 18, 2011, 12:01:57 AM »
good question, isles. good question, indeed. money power. its a sad fact. truly. money is the global influential factor, money influences politics and even (unfortunately) blinds justice.

large corporations such as marlboro even fund 'anti-smoking' commercials. hypocrisy eh? lol.

i'll tell you one thing, i know some pulmonologists (doctors who specialize in the lung & respiratory system) who smoke. yes. hypocrisy.
a doctor who smokes and yet tells patients not to smoke. lol.

cheers.

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Scarb

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Re: Smoking causes gene damage in minutes
« Reply #4 on: January 18, 2011, 02:58:09 AM »
good question, isles. good question, indeed. money power. its a sad fact. truly. money is the global influential factor, money influences politics and even (unfortunately) blinds justice.

large corporations such as marlboro even fund 'anti-smoking' commercials. hypocrisy eh? lol.

i'll tell you one thing, i know some pulmonologists (doctors who specialize in the lung & respiratory system) who smoke. yes. hypocrisy.
a doctor who smokes and yet tells patients not to smoke. lol.

cheers.

the power of IRONY?  ;D

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Scarb

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Re: Smoking causes gene damage in minutes
« Reply #5 on: January 18, 2011, 03:01:34 AM »
Sa langit wlay sigarilyo apan tuay Shabu,datz why magyuzi ta dinhi.. ;D

Sa langit wlay beer apan tua si San Miguel..datz why prosst..che3r§   hik§

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Logical consequences are the scarecrows of fools and the beacons of wise men. ~ Thomas Henry Huxley~

Romans 10:9
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Re: Smoking causes gene damage in minutes
« Reply #6 on: January 18, 2011, 05:08:04 AM »
Sa langit wlay sigarilyo apan tuay Shabu,datz why magyuzi ta dinhi.. ;D

Sa langit wlay beer apan tua si San Miguel..datz why prosst..che3r§   hik§

 tarunga nang imong pag panaygon,,,,aron dako dako ang ihatag sa tagbalay ;)

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Scarb

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Re: Smoking causes gene damage in minutes
« Reply #7 on: January 18, 2011, 05:28:29 AM »
tarunga nang imong pag panaygon,,,,aron dako dako ang ihatag sa tagbalay ;)

ajehehe bahalag wlay wawartz ihatag bazta naay TR..tungab napod lui..!  :P

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Logical consequences are the scarecrows of fools and the beacons of wise men. ~ Thomas Henry Huxley~

Romans 10:9
"That if you shall confess with your mouth the Lord Jesus, and shall believe in your heart that God has raised him from the dead, you shall be saved."
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hubag bohol

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Re: Smoking causes gene damage in minutes
« Reply #8 on: January 18, 2011, 08:26:30 AM »
the power of IRONY?  ;D

He he, daghang nangapangag aning irony...  ;D

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hubag bohol

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Re: Smoking causes gene damage in minutes
« Reply #9 on: January 18, 2011, 08:29:39 AM »
Sa langit wlay sigarilyo apan tuay Shabu,datz why magyuzi ta dinhi.. ;D

Sa langit wlay beer apan tua si San Miguel..datz why prosst..che3r§   hik§

Kahinumdom man lang ta ani sa thread ni Bay Vistabel, ngano kunong way magdalig adto sa langit...

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