Comorbidity of DSM-IV Personality Disorders in unipolar and
bipolar affective disorders: a comparative study.
Schiavone P, Dorz S, Conforti D, Scarso C, Borgherini G.
Affective Disorders Unit, Casa di Cura Parco dei Tigli, Padova, Italy.
The aim of this study was to compare the prevalence of Personality Disorders
assessed by Structured Clinical Interview for Axis-II in 155 inpatients diagnosed
with Unipolar Disorder vs inpatients with Bipolar Disorder (39). The most
frequent Axis II diagnoses among Unipolar inpatients were Borderline (31.6%),
Dependent (25.2%), and Obsessive-Compulsive (14.2%) Personality Disorders.
Among Bipolar inpatients, the most prevalent personality disorders were
Borderline (41%), Narcissistic (20.5%), Dependent (12.8%), and Histrionic
disorders (10.3%). Using chi squared analysis, few differences in distribution
emerged between the two groups: Unipolar patients had more recurrent
Obsessive-Compulsive Personality Disorder than Bipolar patients (chi(1)2=6.24,
p<.005). Comorbid Narcissistic Personality Disorder was significantly more
frequent in the Bipolar than in the Unipolar group (chi(1)2=6.34, P<.01).
Considering the three clusters (DSM-IV classification), there was a significant
difference between the groups, Cluster C (fearful, avoidant) diagnoses being more
frequent in the Unipolar than in the Bipolar group (48.4% vs 20.5%, respectively).
Cluster B (dramatic, emotionally erratic) diagnoses were found more frequently in
patients with Bipolar Disorders (71.8% vs 45.2% in Unipolar patients,
chi(2)2=10.1, p<.006). The differences in the distribution and prevalence of
Personality Disorders between the two patient groups are discussed.
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