Lifting weights releases myokines, signaling proteins produced by muscle cells, which have beneficial effects on inflammation, blood sugar regulation and brain health.
Myokines act as messengers, communicating between muscles and other organs, impacting various bodily functions.
Myokines are released during muscle contractions when weight training and play a crucial role in mediating the positive effects of exercise.
Myokines, particularly IL-6, have been shown to reduce inflammation, both acute inflammation and chronic low-grade inflammation associated with physical inactivity, aging or metabolic disorders.
Additionally, myokines, including IL-6 and irisin, can improve glucose uptake in muscle, enhance insulin sensitivity, and regulate glucose metabolism in the liver and pancreas.
Some myokines, like FGF21, can cross the blood-brain barrier and have been shown to improve cognitive performance, reduce inflammation and help protect against neurodegenerative diseases.
PMID: 39376657
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