The latex is used to cure certain varieties of herpes and wounds caused by poisonous fish.
The latex of the leaves and fruits is used to produce purging.
The leaves are used as a sudorific to treat headache.
The dried leaves were formerly used as a substitute for opium or mixed with it.
The leaves, applied externally, are said to be antirheumatic.
They are applied to cure colds, coughs, fever and fungal and bacterial diseases.
Root scrapings, or the leaves, have been mixed with water and drunk to cure dysentery or diarrhoea.
The roots are antiasthmatic, antidote, antiemetic and diuretic.
The crushed root, mixed with coconut water, is drunk daily to treat urinary tract infections.
The roots are used as a poultice on boils.
The fruits are emetic.
Stem bark material of this species was active against tumor cell cultures. The main alkaloids are tylocrebrine and tylophorine.

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