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CMV Infection

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CMV Infection
« on: June 06, 2012, 02:45:41 PM »

The prevalence of CMV infection among donors is very high (approaching 100% in many series). CMV infection represents a major clinical risk mostly for immunocompromised recipients and neonates. Leukocyte filters can reduce the risk of transmission.

Very rare (1/514,000–2,993,000 units transfused). Use of leukocyte filters can further decrease risk of transmission.

source: Clinical Access Pocket

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Re: CMV Infection
« Reply #1 on: June 06, 2012, 03:32:48 PM »
Mike, that's the reason why patients receiving organ donation are given prophylactic ANTIBIOTICS (usually: AMOXICILLIN, CEPHALOSPORIN, VANCOMYCIN, TRIMETHOPRIM SULFAMETHAXAZOLE) prior to surgery. In case of CMV, patients are also given a bolus of ANTI-VIRAL medication prophylactically (usually: GANGCYCLOVIR, ZIDOVUDINE, RIBAVIRIN).

The administration of prophylactic drugs significantly reduces the incidence of surgery-related bacterial and viral infection.


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