In the 14th century the growth of maritime trade and the recognition that plague was introduced by ships returning from the Levant led to the adoption of quarantine in Venice. It was decreed that ships were to be isolated for a limited period to allow for the manifestation of the disease and to dissipate the infection brought by persons and goods. Originally the period was 30 days, trentina, but this was later extended to 40 days, quarantina. The choice of this period is said to be based on the period that Christ and Moses spent in isolation in the desert. In 1423 Venice set up its first lazaretto, or quarantine station, on an island near the city. The Venetian system became the model for other European countries and the basis for widespread quarantine control for several centuries. --
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