One of the most infamous cases was Charles Whitman, the so-called Texas Sniper. The University of Texas student killed his wife and mother, then killed 13 others shooting from a tower in Austin in 1966; 33 others were wounded.
After an autopsy, doctors revealed he had glioma blastoma. "Indeed, much of his behavior was attributed to that," said Barrow.
"It's not rare for people with brain tumors to present, among other things, a personality change," said Barrow. "Sometimes it's subtle and noticed only by loved ones."
John Graves' tumor was located in the frontal lobe, which controls personality and emotion -- "the things that make you who you are," according to his wife.
His short-term memory had started to fail and "he honestly didn't know where he was and how to get home," she said. "He'd be on the phone and not know who he was talking to.
"I thought maybe he was doing drugs and drinking or he was depressed and gambling," she said.
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