Vitamin D appears to help preserve telomere length.
Several studies have found that higher levels of vitamin D are associated with longer telomeres. One major clinical trial, known as the VITAL trial, found that daily vitamin D supplementation significantly slowed down the rate of telomere shortening over a four-year period. This effect was estimated to be equivalent to about three years of less biological aging.
The protective effect might be due to vitamin D's influence on an enzyme called telomerase. Some studies suggest that vitamin D can boost the activity of telomerase, which is the enzyme responsible for adding DNA back to the ends of chromosomes, helping to maintain their length.
Vitamin D is also known for its anti-inflammatory properties, which may help protect telomeres from damage caused by oxidative stress and inflammation.
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