How effective is it?Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
The effectiveness ratings for BIOTIN are as follows:
Likely effective for...
Treating and preventing biotin deficiency. Symptoms of deficiency include thinning of the hair (often with loss of hair color), and red scaly rash around the eyes, nose, and mouth. Other symptoms include depression, listlessness, hallucinations, and tingling in the arms and legs. There is some evidence that cigarette smoking may cause mild biotin deficiency.
Possibly ineffective for...
Skin rash in infants (seborrheic dermatitis).
Insufficient evidence to rate effectiveness for...
Hair loss. There is some preliminary evidence that hair loss can be reduced when biotin is taken by mouth in combination with zinc while a cream containing the chemical compound clobetasol propionate (Olux, Temovate) is applied to the skin.
Diabetes. Biotin alone doesn’t seem to affect blood sugar levels in people with type 2 diabetes. However, there is some evidence that a combination of biotin and chromium (Diachrome, Nutrition 21) might lower blood sugar in people with diabetes, whose diabetes is poorly controlled by prescription medicines.
Diabetic nerve pain. There is some evidence that biotin can reduce nerve pain in people with diabetes.
Brittle fingernails and toenails. Biotin might increase the thickness of fingernails and toenails in people with brittle nails.
Other conditions.
More evidence is needed to rate biotin for these uses.
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