Her husband, Umberto di Maio, said the family had been praying to John Paul II, who had died just a few months before, when Esposito was diagnosed in July 2005. But as di Maio recounts it, John Paul appeared to him in a dream one night and said he couldn't help Esposito but showed a photo of a slim, bespectacled prelate who could.
Di Maio said he wasn't able to identify the priest until he saw Pius on the cover of a Catholic magazine a week later. As soon as he did, the family began fervently praying to Pius.
The family became convinced of Pius' intervention when Esposito's case was referred to a cancer specialist in Rome, an atheist who, after reviewing her charts, asked the family if they believed in God.
When di Maio replied they did, the doctor said: "Then pray, because she needs it," di Maio recounted.
Esposito, who still keeps the same dog-eared photocopy of Pius in her book of prayers, says she and her doctors were stunned when her PET scan, which detects lingering traces of cancer, came out clean after her six-week chemo cycle at the Umberto I hospital in the southern city of Nocera, near Salerno.
Her doctor, she said, was flabbergasted: "'Do you see this? It's clean! How is it possible?'" Esposito recalled Dr. Alfonso Maria D'Arco, head of oncology and hematology at Umberto I, as saying.
"And spontaneously I said to him, 'Doctor, doctor, isn't it possible that it came from above?" she said, pointing heavenward.
"No, no, no. Don't say shocking things," she said he responded.
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