Altered miRNA Expression as Diagnostics and Therapeutics for Adrenocortical CarcinomasThis technology describes that altered human miRNA expression such as miRNA-483 and miRNA 100 can accurately predict if a patient's adrenal cortex tumor is benign or malignant. Adrenocortical carcinomas (ACC) are rare but aggressive cancers and typically have a poor prognosis. Currently, there are limited options for molecular diagnosis to distinguish malignant tumors from benign tumors of this type. As a result there are few treatment strategies for ACC.
Preliminary results suggest that altering the expression of this miRNA in ACC cells can effect cancer cell growth. Therefore, inhibiting a miRNA may serve as a therapeutic option for ACC.
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Topic: Science News: Altered miRNA Expression as Diagnostics and Therapeutics for Adrenocortical Carcinomas (Read 336 times)